|
Catalogue
Number
|
Product
|
Order number / Unit
|
|
|
1640
|
(R,S)-N-Desmethyl PK11195
|
1640.0001: 1 mg per vial
1640.0002: 2 mg per vial
Please inquire for customized
filling and bulk quantities.
|
|
|
Precursor for (R,S)-[N-Methyl-11C-]PK11195
|
|
|
|
|
|
|
|
|
Molar Mass: 338.83
|
|
|
C20H19ClN2O
|
|
|
[124236-61-9]
|
|
|
|
|
|
Colourless crystals packaged in dark glass crimp cap vials.
|
|
|
|
|
|
|
|
|
Purity: > 95 %
|
|
|
Certificates:
CoA; 1H NMR spectrum
|
|
|
Chemical Name:
CA index name: 3-Isoquinolinecarboxamide, 1-(2-chlorophenyl)-N-(1-methylpropyl),-(R,S)
|
|
|
Synonymes:
1-(2-Chlorophenyl)-N-(1-methylpropyl)-isoquinoline-3-carboxamide-(R,S)
|
|
|
Literature:
1. Camsonne R. et al. Synthesis of N-[11C] methyl, N-(methyl-1-propyl), (chloro-2-phenyl)-1-isoquinoline carboxamide-3 (PK11195): A new ligand for peripheral benzodiazepine receptors. J. Labelled Compd. Radiopharm. 1984, 21, 985-991.
|
|
|
2. Hashimoto K. et al. Synthesis and evaluation of 11C-PK11195 for in vivo study of peripheral-type benzodiazepine receptors using positron emission tomography. Ann. Nucl. Med. 1989, 3, 63-71.
|
|
|
3. Shah F. et al. Synthesis of the Enantiomers of [N-methyl-11C]PK 11195 and Comparison of their Behaviours as Radioligands for PK Binding Sites in Rats. Nucl. Med. Biol. 1994, 21, 573-581.
|
|
|
4. Cremer J.E. et al. The Distribution of Radioactivity in Brains of Rats Given [N-methyl-11C]PK11195 In Vivo After Induction of a Cortical Ischaemic Lesion. Int. J. Rad. Appl. Instrum. B, 1992, 19, 159-166.
|
|
|
|
|
|
date of product catalogue issue:
05 April 2012
|