ABX Datasheet Product Number 1643

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ABX advanced biochemical compounds


Catalogue Number	Product	Order number / Unit

1643	(+)-HNO hydrochloride	1643.0001: 1 mg per vial 1643.0010: 10 mg per vial Please inquire for customized filling and bulk quantities.
	Precursor for [¹¹C]-(+)-PHNO Precursor for [¹⁸F]-(+)-F-PHNO


	Molar Mass: 241.71
	C₁₂H₁₅NO₂ ⋅ HCl
	[858517-21-2]

	Beige solid packaged in dark glass screw cap vials.


	Purity: > 95 %
	Certificates: CoA; ¹H NMR spectrum
	Chemical Name: CA index name: 2H-Naphtho[1,2-b]-1,4-oxazin-9-ol, 3,4,4a,5,6,10b-hexahydro-, hydrochloride (1:1), (4aR,10bR)
	Synonymes: (4aR,10bR)- 3,4,4a,5,6,10b-hexahydro-2H-Naphth[1,2-b]-1,4-oxazin-9-ol, hydrochloride; (+)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-β][1,4]oxazin-9-ol hydrochloride; (4aR,10bR)-3,4,4a,5,6,10b-Hexahydro-2H-Naphth[1,2-β]-1,4-oxazin-9-ol, hydrochloride; (+)-HNO [¹¹C]-(+)-PHNO = [¹¹C]-(+)-4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol [¹⁸F]-(+)-F-PHNO = [¹⁸F]-(+)-4-Fluoropropyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol
	Literature: 1. Wilson et al. [¹¹C]-(+)-4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol as a Potential Radiotracer for in Vivo Imaging of the Dopamine D2 High-Affinity State with Positron Emission Tomography. J. Med. Chem. 2005, 48, 4153-4160.
	2. Boileau et al. Decreased binding of the D3 dopamine receptor-preferring ligand [¹¹C]-(+)-PHNO in drug-naīve Parkinson's disease. Brain, 2009, 132, 1366-1375.



	date of product catalogue issue: 05 April 2012

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