ABX Datasheet Product Number 1645

ABX advanced biochemical compounds


Catalogue Number	Product	Order number / Unit

1645	(+)-PHNO hydrochloride	1645.0001: 1 mg per vial 1645.0010: 10 mg per vial Please inquire for customized filling and bulk quantities.
	Reference standard for [¹¹C]-(+)-PHNO


	Molar Mass: 283.79
	C₁₅H₂₁NO₂ ⋅ HCl
	[99705-65-4]

	Off-white solid packaged in dark glass screw cap vials.


	Purity: > 95 %
	Certificates: CoA; ¹H NMR spectrum
	Chemical Name: CA index names: 2H-Naphtho[1,2-b]-1,4-oxazin-9-ol, 3,4,4a,5,6,10b-hexahydro-4-propyl-, hydrochloride (1:1), (4aR,10bR)-; (4aR,10bR)- 2H-Naphth[1,2-b]-1,4-oxazin-9-ol, 3,4,4a,5,6,10b-hexahydro-4-propyl-, hydrochloride, (4aR-trans)-
	Synonymes: Noxazinal hydrochloride, Naxagolide hydrochloride, Nazagolide hydrochloride, Dopazinol hydrochloride, L647339, MK 458, (+)-PHNO hydrochloride, (+)-4-propyl-9-hydroxynaphthoxazine hydrochloride; [¹¹C]-(+)-PHNO = [¹¹C]-(+)-4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol
	Literature: 1. Wilson et al. [¹¹C]-(+)-4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol as a Potential Radiotracer for in Vivo Imaging of the Dopamine D2 High-Affinity State with Positron Emission Tomography. J. Med. Chem. 2005, 48, 4153-4160.
	2. Boileau et al. Decreased binding of the D3 dopamine receptor-preferring ligand [¹¹C]-(+)-PHNO in drug-naīve Parkinson's disease. Brain, 2009, 132, 1366-1375.



	date of product catalogue issue: 05 April 2012