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Catalogue
Number
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Product
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Order number / Unit
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1646
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(+)-F-PHNO
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1646.0001: 1 mg per vial
1646.0010: 10 mg per vial
Please inquire for customized
filling and bulk quantities.
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Reference standard [18F]-(+)-F-PHNO
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Molar Mass: 265.32
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C15H20FNO2
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[905963-70-4]
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Colourless to off-white solid packaged in dark glass screw cap vials.
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Purity: > 95 %
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Certificates:
CoA; 1H and 19F NMR spectra
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Chemical Name:
CA index name: 2H-Naphtho[1,2-b]-1,4-oxazin-9-ol, 4-(3-fluoropropyl)-3,4,4a,5,6,10b-hexahydro-, (4aR,10bR)-; 2H-Naphth[1,2-b]-1,4-oxazin-9-ol, 4-(3-fluoropropyl)-3,4,4a,5,6,10b-hexahydro-, (4aR,10bR)-
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Synonymes:
[18F]-(+)-F-PHNO = [18F]-(+)-4-Fluoropropyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol
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Literature:
1. Wilson et al. [11C]-(+)-4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol as a Potential Radiotracer for in Vivo Imaging of the Dopamine D2 High-Affinity State with Positron Emission Tomography. J. Med. Chem. 2005, 48, 4153-4160.
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2. Boileau et al. Decreased binding of the D3 dopamine receptor-preferring ligand [11C]-(+)-PHNO in drug-naïve Parkinson's disease. Brain, 2009, 132, 1366-1375.
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3. Wilson et al. Syntheses and in vitro evaluation of fluorinated naphthoxazines as dopamine D2/D3 receptor agonists: radiosynthesis, ex vivo biodistribution and autoradiography of [18F]F-PHNO. Nucl. Med. Biol. 2007, 34, 195-203.
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date of product catalogue issue:
05 April 2012
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