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Catalogue
Number
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Product
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Order number / Unit
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1700
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Desmethylflumazenil
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1700.0001: 1 mg per vial
1700.0002: 2 mg per vial
Please inquire for customized
filling and bulk quantities.
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Precursor for [11C]Flumazenil
Precursor for 5-[18F]Flumazenil ([18F]FEF)
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Molar Mass: 289.26
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C14H12FN3O3
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[79089-72-8]
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Colourless crystals packaged in dark glass crimp cap vials.
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Purity: > 95 %
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Certificates:
CoA; 1H and 19F NMR spectra
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Chemical Name:
CA index name: 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-6-oxo-, ethyl ester
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Synonymes:
8-Fluoro-5,6-dihydro-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester; Desmethyl-FMZ; Ro 15-5528
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Literature:
1. Nagren K. et al. Methylation of amide and thiol functions with [11C]methyl triflate, as exemplified by [11C]NMSP, [11C]flumazenil and [11C]methionine. J. Labelled Compd. Radiopharm. 1998, 41, 831-841.
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2. Maziere M. et al. Synthesis of Ethyl 8-Fluoro-5,6-dihydro-5-[11C]methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate (RO 15.1788-11C): A Specific Radioligand for the In Vivo Study of Central Benzodiazepine Receptors by Positron Emission Tomography. Int. J. Appl. Radiat. Isot. 1984, 35, 973-976.
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date of product catalogue issue:
05 April 2012
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