|
Catalogue
Number
|
Product
|
Order number / Unit
|
|
|
1710
|
Flumazenil
|
1710.0010: 10 mg per vial
1710.0020: 20 mg per vial
1710.0100: 100 mg per vial
Please inquire for customized
filling and bulk quantities.
|
|
|
Reference standard for [11C]Flumazenil
Reference standard for [18F]Flumazenil
|
|
|
|
|
|
|
|
|
Molar Mass: 303.29
|
|
|
C15H14FN3O3
|
|
|
[78755-81-4]
|
|
|
|
|
|
Colourless crystals packaged in dark glass screw cap vials.
|
|
|
|
|
|
|
|
|
Purity: > 95 %
|
|
|
Certificates:
CoA; 1H and 19F NMR spectra
|
|
|
Chemical Name:
CA index name: 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo-, ethyl ester
|
|
|
Synonymes:
8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-Imidazo[1,5-a][1,4]benzo-diazepine-3-carboxylic acid ethyl ester; Anexate; Flumazenil; Flumazepil; Flumenazil; Lanexat; Mazicon; FMZ; Ro 15-1788
|
|
|
Literature:
1. Nagren K. et al. Methylation of amide and thiol functions with [11C]methyl triflate, as exemplified by [11C]NMSP, [11C]flumazenil and [11C]methionine. J. Labelled Compd. Radiopharm. 1998, 41, 831-841.
|
|
|
2. Suzuki K. et al. Computer-Controlled Large Scale Production of High Specific Activity [11C]Ro 15-1788 for PET Studies of Benzodiazepine Receptors. Int. J. Appl. Radiat. Isot. 1985, 36, 971-976.
|
|
|
3. Maziere M. et al. Synthesis of Ethyl-8-fluoro-5,6-dihydro-5-[11C]methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate (RO 15.1788-11C): A Specific Radioligand for the In Vivo Study of Central Benzodiazepine Receptors by Positron Emission Tomography. Int. J. Appl. Radiat. Isot. 1984, 35, 973-976.
|
|
|
|
|
|
|
|
|
date of product catalogue issue:
05 April 2012
|