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Catalogue
Number
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Product
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Order number / Unit
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2870
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2-O-(Trifluoromethylsulfonyl)-1,3,5-tri-O-benzoyl-
alpha-D-ribofuranose
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2870.0010: 10 mg per vial
Please inquire for customized
filling and bulk quantities.
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Precursor 1 for [18F]FEAU and [18F]FMAU
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Molar Mass: 594.51
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C27H21F3O10S
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[97614-41-0]
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Yellowish oil packaged in dark glass crimp cap vials.
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Purity: > 95 %
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Certificates:
CoA; 1H and 19F NMR spectra
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Chemical Name:
CA index name: α-D-Ribofuranose, 1,3,5-tribenzoate 2-(trifluoro-methanesulfonate)
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Synonymes:
1,3,5-Tri-O-benzoyl-2-O-(trifluoromethanesulfonyl)-α-D-ribofuranose; (2-O-(Trifluoromethylsulfonyl)-1,3,5-tri-O-benzoyl-α-D-ribofuranose)
[18F]FEAU = 2′-[18F]Fluoro-5-ethyl-1-β-D-arabinofuranosyluracil
[18F]FMAU = 2′-deoxy-2′-[18F]Fluoro-5-methyl-1-β-D-arabinofuranosyluracil
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Literature:
1. Blasberg R.G. et al. Synthesis and Evaluation of [18F] Labeled Pyrimidine Nucleosides for Positron Emission Tomography Imaging of Herpes Simplex Virus 1 Thymidine Kinase Gene Expression. J. Med. Chem. 2006, 49, 5377-5381.
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2. Alauddin M.M. et al. Synthesis and evaluation of 2′-deoxy-2′-18F-fluoro-5-fluoro-1-beta-D-arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression. J. Nucl. Med. 2004, 45, 2063-2069.
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3. Alauddin M.M. et al. Stereospecific fluorination of 1,3,5-tri-O-benzoyl-a-D-ribofuranose-2-sulfonate esters: preparation of a versatile intermediate for synthesis of 2′-[18F]-fluoro-arabinonucleosides. J. Fluorine Chem. 2000, 106, 87-91.
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date of product catalogue issue:
05 April 2012
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