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Catalogue
Number
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Product
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Order number / Unit
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4210
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Altropane
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4210.0001: 1 mg per vial
4210.0010: 10 mg per vial
Please inquire for customized
filling and bulk quantities.
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Reference standard for [11C]Altropane
Reference standard for [*I]Altropane
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Molar Mass: 429.27
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C18H21FINO2
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[180468-34-2]
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Colourless to orange solid packaged in dark glass screw cap vials.
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Purity: > 95 %
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Certificates:
CoA; 1H and 19F NMR spectra
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Chemical Name:
CA index name: 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(4-fluorophenyl)-8-[(2E)-3-iodo-2-propenyl]-, methyl ester, (1R,2S,3S,5S)-
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Synonymes:
(E)-N-(1-Iodoprop-1-en-3-yl)-3-β-(4-fluorophenyl)-nortropane-2-β-carboxylic acid methyl ester; (E)-N-(3-Iodoprop-2-enyl)-2β-carbomethoxy-3β-(4-fluorophenyl)-nortropane; 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(4-fluorophenyl)-8-(3-iodo-2-propenyl)-, methyl ester, [1R-[1a,2a,3a,5a,8(E)]]-; IACFT
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Literature:
1. Fischman A.J. et al. [11C,127I] Altropane: a highly selective ligand for PET imaging of dopamine transporter sites. Synapse 2001, 39, 332-342.
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2. Elmaleh D.J. et al. Preparation and biological evaluation of iodine-125-IACFT: a selective SPECT agent for imaging dopamine transporter sites. J. Nucl. Med. 1996, 37, 1197-1202.
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3. Madras B.K. et al. Altropane, a SPECT or PET imaging probe for dopamine neurons: I. Dopamine transporter binding in primate brain. Synapse 1998, 29, 93-104. II. Distribution to dopamine-rich regions of primate brain. Synapse 1998, 29, 105-115 III. Human dopamine transporter in postmortem normal and Parkinson′s diseased brain. Synapse 1998, 29, 116-27.
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date of product catalogue issue:
05 April 2012
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